GOG-3043 ROCC: A Randomized Controlled Trial of Robotic versus Open Radical Hysterectomy for Cervical Cancer (ROCC trial)

This is a randomized controlled trial to compare survival for patients who underwent robotic assisted laparoscopy versus open radical hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.

Inclusion Criteria

  • Patient must have histologically confirmed adenocarcinoma (usual/classic/NOS), squamous cell carcinoma, adenosquamous carcinoma
    (Including glassy cell)
  • Patient must be FIGO Stage IA2, IBI, IB2 (2018 staging) without evidence of definitive parametrial, vaginal, nodal or distant metastases on exam or imaging.
  • Patient must be suitable surgical candidate with preoperative assessments such as labs and EKG performed per institutional standard.
  • Patient must have ECOG performance status 0-1.

Exclusion Criteria

  • Patient with inability to receive an MRI.
  • Patients with evidence of metastatic disease (imaging or histologically positive lymph nodes).
  • Patients with a history of prior pelvic or abdominal radiotherapy.
  • Patients with a prior malignancy < 5 years from enrollment with the exception of non-melanoma skin cancer.
  • Patient compliance and geographic proximity that do not allow adequate follow-up.

This study is for patients age 18 Years and older.

Available at: Hartford Hospital, Manchester and HOCC

Cancer Clinical Research Office